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by UseofWeapons1 1080 days ago
Curious, do you have a source for this?

Are PFAS primarily concentrated in the bloodstream?

2 comments

I'm not sure if it's concentrated in blood or not but as I understand it it's mostly protein bound which means it probably moves into and out of tissues easily but not out the kidneys or into stool.

https://www.wbur.org/news/2023/02/16/pfas-biology-blood-new-...

Someone else's already replied with the Australian fire fighter study which shows that blood levels fall with donation. If movement isn't free into and out of the "compartments" then it's possible end organ damage continues unabated even as blood levels dilute.

But it seems likely that donating does reduce concentrations in organs as the PFAS move back into blood.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994130/

It seems like donating plasma is even more effective.