[_nhynes]

This study has some nice data in it, but they didn't really start with a very strong hypothesis, to my understanding. The paper starts with a citation about stress being inversely associated with telomere length, and proposes that psilocybin decreases psychological stress, but then goes on to demonstrate decreases in entirely different in vitro physiological stress markers. How is one to tell that this isn't just cherry-picking dependent variables that look good?

[amts]

State of senescence in cells can also be caused by mechanical stress [1], this is the basis of senescent cell formation in osteoarthritis etc. So maybe psilocybin is somehow generalizing.

[1]. https://www.ihmc.us/stemtalk/episode-122/ (47:30)