[edrxty]

There's very little evidence it causes any problems. Some of these medications have been in use since the 60s and most have at least 20 years of data behind them.

>neurotoxic amphetamines

That's deliberately loaded terminology. Amphetamines are neurotoxic but not at the doses used therapeutically (obviously). Everything is neurotoxic at a high enough dose.

>The drugs own warnings are pretty bad

All drugs have pretty bad warnings:

Each year, the side effects of long-term NSAID use cause nearly 103,000 hospitalizations and 16,500 deaths. More people die each year from NSAIDs-related complications than from AIDS and cervical cancer in the United States.

https://www.sciencedaily.com/releases/2005/01/050111123706.h...