Organized crime will always exist as long as there is human demand for something illegal, it's how aggressively you manage it (investigate, jail, or in some countries, execute, depending on the crime, measured harm, etc).
Organized crime at scale only ever exists due to the government manifesting it through a prohibition that shouldn't have been put into place.
The organized at scale (beyond just a gang in a neighborhood) aspect of it requires considerable ongoing capital infusion, which you can only get from a sustainable extraction of economy. It's that pocket of black market economy that is always created by government action, without exception. Every large gang operation in the US rides on top of government prohibition or otherwise preys on regressive regulation.
The war on drugs being the greatest example in recorded history.