I use Android with work profile and just turn it off at the end of the day (actually have it automatically scheduled). Definitely took some discipline at first but now I'm really disconnected on days off.
Different profiles do you no good. Under US law, if there's an investigation against your employer, you might be required to hand over any device that you used to access your work email, or other data. That's why your work phone should be a separate device, not just a profile.
I doubt any search warrant will respect simple ownership. If the police deem something evidence then under US law you will basically never see it again...