[sfjailbird]

> it's interesting to hear comments from people saying the "wanted to punch everyone", etc, when they started TRT. At TRT doses, most men experience a sense of calm and confidence, rather than irascibility.

Adding testosterone also raises estrogen (estradiol) which causes irritability. It is hard to find a balance where both are in check.

[leroy_masochist]

That's why you get your blood work done and titrate anastrozole, which a good TRT-prescribing office is going to do without you asking. I would disagree with your contention that it is hard to dial in estradiol. It is, in fact, a very straightforward process based off of blood labs.

[ajcp]

It's not hard at all if you do initial bloodwork to establish baseline estradiol. After that and depending on the results the TRT regime should include an estrogen blocker to negate a rise.