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by cqz 1102 days ago
Possible but untested. You may be interested to see this recent study that draws a mechanistic link (broadly, microglial inflammation) between the symptoms of long covid and "chemobrain" following chemotherapy [0]. The authors do suggest treatments proposed to restore cognition post-chemotherapy may also be applicable to long covid, e.g. metformin [1].

[0] https://www.cell.com/cell/fulltext/S0092-8674(22)00713-9

[1] https://www.nature.com/articles/s41591-020-0985-2

1 comments

Metformin is looking like the aspirin of the 21st century.
Nir Barzilai and a team of researchers are leading a large clinical trial to test the benefits of metformin in slowing the aging process, which is upstream of so many diseases that yeah, it could just be a cheap cure-all. Sadly requires a prescription in the US. But berberine is the off-the-shelf equivalent.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347426/

Yeah agreed. Is berberine really an equivalent though if the mechanisms are different and the not knowing metformin’s complete mechanism although it has a pleitropic effect? Metformin is heavily studied in comparison too.