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by bitemaja 1104 days ago
I think real risk is testing these chimera viruses on mice with humanized cells.

Letting viruses evolve in-vivo is the problem especially when they are so viral.

There needs to be limitations on what R is allowed to be produced in-vivo, even more so because calculating the risk of virality of the outbreak is trivial if in-vitro studies are done.

1 comments

Chimera virus. You mean like a spike protein expressing VSV? Do you think that (pseudo virus) requires a higher or lower BSL certification to work with than bonafide Coronavirus? Why?

And why are you worried about humanized mice and not human cell lines like HEK or CALU? Why not primary cells or organoids? Somewhere the “Outbreak” monkey is crying.

I admit that I am being a bit snarky and passive aggressive here; but for the past few years I have watched people butcher bioscience in online discussions. Imagine being a classically trained pianist and having to watch people misattribute all of Mozart’s work to Brahms. It is enough to drive anyone mad.

A classically trained pianist's profession does not carry the risk of killing millions of people! There is zero proof outside of circumstantial conjecture that SARS2 has a natural origin. Up to 20 million people have died due to an animal virus modified to be highly infectious towards humans and you expect everyone to just take your word for it?

I mean it sucks if it hurts your career or impacts your profession, but highly dangerous work needs to be reviewed and banned if need be!

Humanity > Your personal career