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You're right that Daszak and the Ecohealth Alliance are culpable, but it must be noted that various USG orgs were not supportive of his actions > The report he finally did submit stated that scientists planned to create an infectious clone of Middle East Respiratory Syndrome (MERS), a novel coronavirus found in dromedaries that had emerged in Saudi Arabia in 2012 and killed 35% of the humans it infected. The report also made clear that the NIH grant had already been used to construct two chimeric coronaviruses similar to the one that caused Severe Acute Respiratory Syndrome (SARS), which emerged in 2002 and went on to cause at least 774 deaths worldwide. (A chimeric virus is one that combines fragments of different viruses.) These revelations prompted the NIH’s grant specialists to ask a critical question: Should the work be subject to a federal
moratorium on what was called gain-of-function research? > But the [2015 research paper he cited](https://www.nature.com/articles/nm.3985) was not particularly reassuring. In it, Shi Zhengli and a preeminent coronavirus researcher at the University of North Carolina, Ralph Baric, mixed components of SARS-like viruses from different species, and created a novel chimera that was able to directly infect human cells. (Baric did not respond to written questions seeking comment.) > If anything, the MERS study Daszak proposed was even riskier. So he pitched a compromise to the NIH: that if any of the recombined strains showed 10 times greater growth than a natural virus, “we will immediately: i) stop all experiments with the mutant, ii) inform our NIAID Program Officer and the UNC [Institutional Biosafety Committee] of these results and iii) participate in decision making trees to decide appropriate paths forward.” > This mention of UNC brought a puzzled response from an NIH program officer, who pointed out that the proposal had said the research would be performed at the WIV. “Can you clarify where the work with the chimeric viruses will actually be performed?” the officer wrote. Ten days later, with still no response from Daszak, the program officer emailed him again. On June 27, Daszak responded, buoyant as ever: > “You are correct to identify a mistake in our letter. UNC has no oversight of the chimera work, all of which will be conducted at the Wuhan Institute of Virology…. We will clarify tonight with Prof. Zhengli Shi exactly who will be notified if we see enhanced replication…my understanding is that I will be notified straight away, as [principal investigator], and that I can then notify you at NIAID. Apologies for the error!” > Allowing such risky research to go forward at the Wuhan Institute of Virology was “simply crazy, in my opinion,” says Jack Nunberg, director of the Montana Biotechnology Center. “Reasons are lack of oversight, lack of regulation, the environment in China,” where scientists who publish in prestigious journals get rewarded by the government, creating dangerous incentives. “So that is what really elevates it to the realm of, ‘No, this shouldn’t happen.’” In general, his actions make clear he's much more aligned with the Chinese government than the US, so extending Daszak to US govt purely based off of nationality seems unjust. > On January 30, Daszak went on CGTN America, the U.S. outpost for Chinese state television, and said two things that proved to be spectacularly wrong. “I’m very optimistic…that this outbreak will begin to slow down,” he said. “We’re seeing a small amount of human-to-human transmission in other countries, but it’s not uncontrollable." He went on to conclude that the Chinese government was taking all necessary steps “to be open and transparent, and work with WHO, and talk to scientists from around the world, and where necessary, bring them in to help. They’re doing that. It’s exactly what needs to happen.” |