I left when Twitter killed off Tweetbot and I‘m happy I did it. Colleagues of mine don‘t want to go without their dev bubble though. It‘s time for a better tool to catch-up to the newest stuff.
I also left Twitter when Tweetbot died, but only because I can’t use Twitter without a chronological timeline and keyword filtering. My impression is that third party Reddit apps had some nice quality of life features, but their main purpose wasn’t to literally alter the underlying content. Happy to be proven wrong though.