[tonymillion]

What’s the LD50 of a huge grain of salt.

While the mouse example of 1000mg/kg is ridiculously high, the monkey trial used 250mg/kg.

Assumption time: assume a 67kg human who consumes 3 cans of redbull a day (not especially unusual). they are ingesting 9000mg (total) per day, which comes out 135mg/kg. Given the easy availability of Taurine supplements in almost any pharmacy it’s not a stretch to see this pushed significantly higher.

Added to the above, this was an initial trial, and it’s very possible the therapeutic levels of Taurine supplementation may be significantly lower (there appeared to be a correlation of health and life extension between the mice and monkeys even with the significant difference in dosages) it’s very possible that the 3 can of red bull dosage is efficacious. Of course that could be mitigated by the high levels of sugar and caffeine but that is outside of the scope of this conversation.

To summarize : 250mg/kg was efficacious in monkeys and no lower bound was determined, it’s possible the amount of Taurine in 3 cans of redbull (assume 9000mg) per day is within the clinically effective range.