[hedora]

Every time one if these stories pops up, I feel compelled to point out that artificial sweeteners have been tied to weight gain, so unless you are diabetic, there’s no reason to ingest them.

In general, they cause your metabolism to slow down, and make you feel hungrier. Giving them to mice on calorie restricted diets causes weight gain and lethargy in the mice.

Giving a subjectively identical amount of sugar to the mice (on top of the calorie restricted diet) causes less weight gain than the artificial sweeteners. (Because the mice stay active.)

[n8henrie]

Source for "metabolism slowing down" (in humans)?

While your claims are fairly popular, AFAIK there is no evidence to suggest that non-nutritive sweeteners cause weight gain in humans. They are highly associated with weight gain, likely because people likely to choose diet beverages are people who have difficulty with weight gain in the first place.

Murine models are not particularly generalizable to humans, particularly when it comes to diet and nutrition.

[hedora]

https://www.healthline.com/nutrition/artificial-sweeteners-a...

[foxyv]

It seems like the jury is still out on this. I get the impression, like most nutrition research, the answer will be "It's complicated."

> Some researchers believe that artificial sweeteners don’t satisfy people’s biological sugar cravings in the same manner as sugar and could lead to increased food intake. Still, the evidence is mixed.

> The strong sweetness of artificial sweeteners may cause you to become dependent on sweet flavor. This could increase your desire for sweet foods in general.

> Some observational studies link artificial sweeteners to weight gain, but evidence is mixed. Controlled studies suggest that artificially sweetened drinks don’t cause weight gain and may even aid weight loss.

[numinoid]

Do you have any evidence of these claims? The research I'm aware of strongly contradicts your initial statement.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744961/