[DoingIsLearning]

For carpal tunnel related injuries, alternating positions between mouse and keyboard will provide intermitent relief to the wrist tissues.

For shoulder/rotator cuff related injuries resting your forearm without weight bearing will provide relief, so repeatedly alternating mouse and keyboard will probably cause strain in those tissues.

Unfortunately the term RSI is a huge bag to say some non recovering 'chronic inflammation' which is not particularly helpful in these discussions.