The big cloud providers attempt to detect and stop crypto mining. I'm not sure if there are ways around it, but if so, they probably involve mining incredibly inefficiently.
Personally I would look into standing up one of the popular AI models like stable diffusion and running a paid service on it.
I think this was a lot of people's first thought as well, but maybe we can brainstorm some other uses that provide a more direct benefit to persons in need, dare I say to society.