[VagueMag]

> Overall, the relatively higher intra-host diversity among vaccinated individuals and the detection of immune-escape mutations, despite being rare, suggest a potential vaccine-induced immune pressure in vaccinated individuals.

[jleyank]

Pretty much everything puts evolutionary pressure on the virus. If the host keels over 1s after infection, that line's going to die out. If the antibodies from vaccination/infection target an invariant portion, the virus might effectively die out (polio, measles, etc). Ideally, between vaccination and infection we've proceeded to an equilibrium - the nasties have been outcompeted or died out and (way) fewer people have been keeling over. If/when Covid truly behaves like the flu it will be another of the coronaviruses causing colds of varying severity.