Unfortunately, yes. Employers, and the non-technical gateways in particular, still have the mindset of "reject for anything, weeding people out means I'm doing my job!"
Make yourself look so valuable that they wouldn't dream of rejecting you for some invented reason. If front-line resume screeners are the issue, get an existing employee to submit your resume and vouch for you and get buy-in from their boss. That way HR can't reject you on a flimsy basis.