[wizzwizz4]

Ketamine is definitely addictive for a lot of people.

Rapamycin isn't one I've heard of before, but it looks like a does-lots-of-things drug: Wikipedia says it's an immunosuppressant. I'd recommend against DIYing that for a different reason.

[radicaldreamer]

Ketamine at the doses prescribed for treating depression has low addictive potential.

The doses used recreationally are multiples of what is regimen for anti-depressive effects.