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by amanaplanacanal 1124 days ago
Please point us to some science about this, because of that is true, it’s a pretty big deal.
2 comments

There's lots. Here's one that tested sugar+sweetener, note the decrease in insulin clearance when sweeteners are consumed, vs just sugar:

sucralose ingestion caused 1) a greater incremental increase in peak plasma glucose concentrations (4.2 ± 0.2 vs. 4.8 ± 0.3 mmol/L; P = 0.03), 2) a 20 ± 8% greater incremental increase in insulin area under the curve (AUC) (P < 0.03), 3) a 22 ± 7% greater peak insulin secretion rate (P < 0.02), 4) a 7 ± 4% decrease in insulin clearance (P = 0.04), and 5) a 23 ± 20% decrease in SI (P = 0.01).

https://diabetesjournals.org/care/article/36/9/2530/37872/Su...

It's anecdata but I've seen similar - however, it could also be explained by "not taking weight loss seriously if all you do is switch to gallons of diet drink".

And for lots of sodas, caffeine plays, too. It's hard to factor out the various issues that could also be present.