[Colex]

I believe a framework like Bootstrap might be a faster approach at the beginning (honestly, it's a fair approach for the whole lifecycle of a project). You get all the building blocks to get a consistent UI working fairly quick with little to no CSS knowledge. Some times removing the unnecessary flexibility may be a boost to get things out there.

But, at the end of day, the best option will be the one you're most comfortable with.

[WorldMaker]

Also, Bootstrap gives you plenty of copy-and-paste ready examples, including accessibility enhancements. Accessibility can be an after-thought to not just devs, but many designers, but Bootstrap helps put it right up front for the lazy developer.

Anecdotally, I've sometimes seen better quality websites for a lot of the little "polish" things like accessibility (which isn't really "polish", is it?) from the laziest "just use Bootstrap" developers than from the most hardworking Tailwind developer+designer combos.