[_proofs]

i do not know if i would actually agree with this as general advice, even for first timers (assuming healthy and safe settings) -- Strassman [0], paraphrasing as it has been a while, mentions in his findings the difference between psychotic and psychedelic thresholds. psychotic thresholds ~<= 300 mcgs tend to be more stimulant-like with an increased heart rate, and it is my opinion he contends this can be more anxiety inducing than a psychedelic dose, which depresses breathing and eases the heart rate/is less stimulating.

my anec-data is most people taking small doses, while enjoyable, seem to experience more anxiety overall than those who have taken a little more of a plunge (myself included in this) -- increased heart rate can really send people through some weird feedback loops, especially on peak.

perhaps mileage varies.

[0]: Dr. Rick Strassman, DMT: The Spirit Molecule -> this is mostly a clinical study on the effects of DMT but Strassman does have general observational commentary on psychedelics such as LSD.