[reducesuffering]

I think most people would agree that taking carcinogens will more likely reduce your lifespan than the possibility of significantly extending it.

For now, I'd rather bet on very clean air, very clean water, fasting, organic vegetables, green tea, omega 3 fish oil, well monitored sleep, and lots of exercise for longevity.

[tysam_and]

That does feel like an overly simplistic argument. Once again, lots and lots of things feed cancer, it's not as simple as that. There's also a big 'might' clause, which means it's something that's going to take time to understand. For example, IIRC, the role that NR might play in cancers is that it's a very accessible food source for them. However, compared to other factors, this might fade into the woodwork, especially if for example it's used as part of a protocol that lowers the chance of cancer (or at the very least, all-cause mortality) longer term. Ideally, at least.

Maybe an analogy to communicate the concept is that it is like putting a car up on jacks and taking out parts to repair another part. It's possible that it is not where you are long-term, or ideal to do extremely frequently, but it's important to keep the thing maintained and running.

That said, I agree very much on your last sentence as one of the best "simple" routines to get bang for the buck. My thoughts would be weight lifting specifically, chamomile tea at night (apigenin is something else), as well as some broccoli sprouts for NRF2 in there. Other than that I think that's probably the index fund-like strategy to longevity, so we're definitely on the same page there. :D :thumbsup: