[drBonkers]

What do you make of all that in the last link?

At a cursory glance, it seems like the biohackers may simply be poisoning themselves on "fission" days and riding the rebound— eventually habituating to the fission supplements (a la arsenic eaters) so they feel less bad on the fission days (which they attribute to mitochondrial repair).

[tysam_and]

Thanks for taking a gander! It is a very curious thread indeed (especially as you go deeper and deeper into its depths). Might I ask what makes you feel it is poisoning?

It is safe doses of well-known supplements (and works for other swaps in their classes -- like apigenin, sulfuraphane, etc).

Curious to hear though the thoughts on the poisoning line.

[drBonkers]

> Might I ask what makes you feel it is poisoning?

I definitely didn't mean to imply that I necessarily believe its poisoning. Apparently the neurotic and anti-interventionist in me reared its head when reading the thread.

I didn't recognize any of the supplement names, and so I didn't realize they all had reasonable safety profiles (individually?).

I think my point still stands though. From what I saw, the outcomes were deemed positive as a function of subjective reports of well-being, without controls. It seems plausible the protocol is having any range of effects (from negative to null to positive)— I just didn't see anything other than placebo-uncontrolled anecdata.

This is not to discount their efforts! I am truly interested in the subject.

[tysam_and]

I think these are very good points! I understand what you're saying better now. :) <3

[vidarh]

Having lifted weights regularly for years, it's profoundly weird for me to see someone reporting doing curls to failure for even just that period of time without improving their results. While I get the person in question just used that as some curious proxy measure, it makes the whole thing seem counterproductive...