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by cpncrunch 1147 days ago
What do you mean? Previous trials of ketamine for depression didn't involve anaesthesia. They uses low doses of ketamine:

https://pubmed.ncbi.nlm.nih.gov/26578082/

Also, they didn't use any anaesthetic known to have antidepressant properties:

"Anesthesiologists were asked to minimize use of nitrous oxide (N2O), which has reported antidepressant effects22. Agents used for anesthetic maintenance included intravenous propofol and inhaled sevoflurane or isoflurane"