[eludwig]

As someone who has done a ton of drawing both on computers and off, the idea that this was drawn with mouse blows my fricken mind! I can't even imagine the patience needed.

As I recall someone saying once, "Drawing with a mouse is like drawing with a bar of soap." So true.

[johnvanommen]

It was obviously digitized. The illustrator just drew the panels on paper, then digitized them and added some textures. (Source: I bought it in the 80s when it was new.)