Sure. But "if this was scaled up several orders of magnitude, and continued for years, then there would likely be bad side-effects" is a argument against doing pretty much anything. Ever.
It's also a really good argument for not putting all our eggs in one basket and for avoiding total homogenization of the systems by which we live. This is not currently practiced at scale, as anyone who has boarded a plane in one state and lands in identical surroundings in another state can attest.