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by aintgonnatakeit 1139 days ago
The first study has 3 patients. The second study is a little better, but not by much. Both have the same first author. If this were legitimate, some academic medical center in the US would have picked it up. Parkinson’s is a huge target, and this kind of thing makes a career. This is likely on the same level as horse dewormer for COVID.
3 comments

We detached this subthread from https://news.ycombinator.com/item?id=35770871 and marked it off topic. Please don't take HN thread on generic flamewar tangents. This is in the site guidelines:

"Eschew flamebait. Avoid generic tangents."

https://news.ycombinator.com/newsguidelines.html

> This is likely on the same level as horse dewormer for COVID.

That something sounds strange doesn't particularly lead me to question the likelihood of efficacy.

The evidence on something's efficacy leads me to question something's efficacy.

>This is likely on the same level as horse dewormer for COVID

You mean something that's demonstrated to have a statistically significant protective effect in a majority of studies but was attacked mercilessly by the pharma industry and the media they fund because they can't profit from a generic drug like that? https://c19ivm.org/meta.html

Looks great .. dive in (talk to your local professional epidemiologist) and it's a skewed collection of low N studies mixed in with studies in regions with large intestinal parasite issues.

Does horse dewormer do anything significant for large populations in first world countries?

No. (Save for regions with a intestinal parasite problem)

Elsewhere it gets rid of a significant number of parasites, making people healthier, and improving their chances WRT everything else, the common cold, influenza, COVID, etc.

If you have worms, take a dewormer course.

If you don't .. it won't do diddly squat for COVID.

Statistics!! (Sometimes there's correlation but that ain't always causal).

Ivermectin is a protease inhibitor, among other possible mechanisms. They developed Paxlovid to work in a similar way, but it seems to be not effective whatsoever.

Then you have Remdisiv, which definitely killed 10's of thousands of people, if not more. That's the real story of COVID, at least in the US. The countless people that were experimented on with one of the most dangerous drugs to be invented in recent times.