[irskep]

My worry with this kind of thing is that some random dependency will break and there will be no easy solution. Compiling Python to JS seems like a very fragile process. And if people run into bugs, they will need to debug a very specialized and unusual toolchain.

If you're going to go all-in on one language to build an entire SaaS product, JS seems like a much safer choice. There's no Django-for-JS yet, as far as I know, but when there is, it'll be a no-brainer.