[echelon]

Do you have a citation for this?

That number seems within the same order of magnitude as I was expecting, but the fact that this has been quantified is fascinating.

Are there similar numbers for mutations per cell division or averages per year of life?

[cosmojg]

Rates of Spontaneous Mutation (Drake et al., 1998)[1] says that a human's genome accumulates around ~64 new mutations per generation through meiosis alone. Those mutations are propagated into every cell of the newborn baby. Over a lifespan, all cells in the body will mutate at a rate proportional to their division rate, leading to thousands upon thousands[2] of uncorrected mutations per individual, among the trillions which are ultimately corrected by DNA polymerase[3].

[1] https://doi.org/10.1093/genetics/148.4.1667

[2] https://doi.org/10.1038%2Fs41586-022-04618-z

[3] https://doi.org/10.1126/science.aaf9011

[Dylan16807]

https://www.sanger.ac.uk/news_item/increased-mutations-in-ch... here's the most comprehensive article

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548427/ also has some numbers