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by mschuster91 1155 days ago
> Since mice are not humans the gender of the mice might be irrelevant.

Actually, it's not. It's well known that medications can have different effects or different dosage requirements depending on menstrual cycle.

And if you drop out a drug candidate in animal trials because you don't account for genetic and hormonal gender as well as menstrual cycle, you can end up dropping prematurely.