Hacker News new | ask | show | jobs
by moremetadata 1158 days ago
Induced Pluripotent Stem Cells are something oncologists have been looking at to create an unlimited number of T cell's, and PSC comes from the bones, so I wonder if bone health is an indicator of immune system response? Its quite common for people to break bones and the flat bones have the red bone marrow that makes the pluripotent stem cells. They can take Mesenchymal Stem Cells and convert them in the test tube into Induced Pluripotent Stem Cells to then become T Cells in the body, but I think they have as much control over the differention of T Cells once in the body like some oncologists using radioactive iodine for thyroid cancer only to find it dispersed around the body with some congregating in the thyroid and not having teh effect they hoped for.

In todays polluted world I wonder if we dont get enough omega 3's considering the role's they play and the triterpenoid's seem interesting.

The most surprising results I've seen is with a batch of histidine, but subsequent batches didnt solicit the same results which makes me wonder if the 1st batch was something like histidine dipeptides or some other reason like cellular pools being depleted of something. Considering histidine helps immune cells move through tissue to targets, aging suggests histidine levels are depleting even if an individual is healthy.

Same goes with glutathione, in disease and aging, it also depletes to dangerously low levels, problem is bacterial biofilms love it to reactivate themselves and until recently it was thought supplementing was a waste, but recent studies contradict this idea.