I used to be irate when I would read these kinds of off the cuff comments about mars missions / colonization but I've come to realize that in 20 years I'll be able to look back and read these with amusement as I watch live streams of people on Mars doing crazy shit.
I know that Von Braun expected humans to set foot on Mars by the late 1970s. If Von Braun thought that was possible it certainly was, if not for the pivot in budget that occured under Nixon.
For better or worse we're seeing a resurgence in privately funded space exploration which may be the key to making it happen this time.
Radiation on Mars can be resolved in the same way, by living in a cave. I expect the first permanent settlements on Mars will either be in sealed sections of lava tubes or in underground artificial structures.
No chance to survive, hard radiation, rescue would need at least a year.