[Scarbutt]

The only reason real reasons you would want to use Clojure over Python are if you need to work/leverage the Java ecosystem (don't want to use Java/Kotlin) and you want a real multithreaded runtime (no GIL).

[pharmakom]

The language itself is better at expressing complex domains than Python.

[johannboehme]

or when you want immutablity and a functional programming style. or if you prefer manipulating lisp ast instead of wrestling indentation. or if you need somewhat decent performance, or if you need somewhat decent multithreading, etc etc..