Huge fan of Kagi and Orion, though unfortunately I couldn't live without Firefox's Multi Account Containers. I'd hop back to Orion in a heartbeat if they had something comparable.
(And also it's been three months since I used Orion, and development is fast-paced, so things could have changed a lot since then)
Personally, Right now I basically resorted to using several profiles but it only supports 1 profile per window so I end up having sometimes 3 windows at the same time. I still switch from time to time to Firefox but it has actually helped me sometimes to keep focus (I.e work).
I love safari but the ad blocking sucks, having to run stupid stuff on top (AdGuard for Safari)