[trotsky]

Stimulants aren't neurotoxic, specific substances at specific levels are. Methylphenidate's majority of benefit comes from its reuptake inhibition of both dopamine and norepinephrine. While it is also a dopamine releasing agent, it does so at dramatically lower levels than the amphetamine family. The difference turns out to be significant - while they both promote more dopamine activity in the brain, it turns out that preventing the disposal of brain chemicals is generally much safer than promoting their release. As far as I know there aren't real concerns about MPH neurotoxicity.

[rms]

Sorry, yes, I'm suggesting that amphetamine is much more dagnerous than methylphendidate.