[rleigh]

My profiling was on an NXP i.MX8 MPU, which is a A-profile quad core SOC very similar to an RPi. I think it was with a PREEMPT_RT kernel, but I can't guarantee that, but I was fairly shocked at the lack of consistency in I2C timing when doing fairly trivial tasks (e.g. a readout of an EEPROM in a single I2C_RDWR request). You wouldn't see this when doing the equivalent on an M-profile MCU with a bare metal application or an RTOS.

What is acceptable does of course depend upon the requirements of your application, and for many applications Linux is perfectly acceptable. However, for stricter requirements Linux can be a completely inappropriate choice, as can A-profile cores. They are not designed or intended for this type of use.

Profiling this stuff is a really interesting challenge, particularly statistical analysis of all of the collected data to compare different systems or scenarios. I've seen some really interesting behaviours on Linux when it comes to the worst-case timings, and they can occasionally be shockingly bad.