[legitster]

*Very hard to find a young person. But you find enough people after 10-15 years of using who will tell you they have noticed some effects.

I think it's important to point out that marijuana is certainly less dangerous than alcohol and cigarettes. But it's weird how people try to argue that there shouldn't be any sort of moderation when it comes to weed. Like, even alcoholics won't argue that they shouldn't be drunk all of the time.

[clbrmbr]

The longer duration and fat solubility of canabinoids makes the alcohol comparison difficult. Many people have a glass of red wine with dinner daily, and are not drunk in the daytime, but even very light cannabis consumption nightly seems to result in a permanent low-level stonnedness.

[gaganyaan]

Do you have a source for permanent low level stonedness? TBH that sounds completely made up.

[clbrmbr]

I did not intend that as an empirical observation but rather a mathematical pharmacokinetic result of fat-solubility rather than water-solubility. THC is fat-soluble and so has a higher volume of distribution which drives a longer half-life.

(See Shulgin “The Nature of Drugs” pg 132)

And “constant” would be a better word than “permanent”, as certainly it should go away after some weeks of abstinence.