[derefr]

> because the brain is nearly inaccesible, even via the CSF (diffusion is very limited), without very invasive way like trepanation.

If transorbital lobotomy is possible, presumably transorbital endoscopic hydrogel injection would also be possible, no?

Also, what about “going in through the out door” — entering the lymphatic system at the neck, and then endoscoping up into the brain’s glymphatic channels, and further back into the brain itself?