[mwbajor]

Not trying to denigrate your response, people do need to make informed decisions. However, "trust your doctor" / "ask your doctor"? People always say this phrase as a knee-jerk reaction. I think that a scientifically minded board like HN can corroborate my experiences in that: MDs are not scientists, in most cases not up to speed on current research (or any form of "science" or what one might believe as science) and many times the most inept at anything other than following their training. Its a reason medicine is moving at a snails pace and we need more open source or civilian science initiative.

Among our community I say, make your calculations and take your dose. Don't talk to your doctor, you'll receive no usable feedback, instead, report your results.

[Maursault]

> MDs are not scientists

?

Medicine is science.

The definition of “scientist” includes someone learned in science, and so a physician absolutely is a scientist. Traditionally trained physicians learn physics and chemistry, biology, biochemistry and molecular biology, and later, anatomy and physiology basics.

But I suppose if MDs had any brains they would have forgone medical school and just got an HN account. Then they could have known everything instead of merely diseases and drugs.

[mwbajor]

Its hardly a science, you can look up the arguments but I'm not the only one that says this. Covid is over, we can stop worshiping the medical field..

And if trying to take physics and organic chem at a community college during the summer so that the "hard classes" dont pull down their GPA is hardly a training in what you think science is.

I'm not trying to demean them, but its not their job to understand the complexities of these drugs. I know alot of MDs and I can guarantee you they would agree. I've had these conversations with them before. Bottom line, they wouldn't be the first ones to ask if I wanted to experiment on myself with some new chemical.

[ramraj07]

If you trust your doctor so little, go find one you trust? A good doctor should be able to have a level headed conversation about things like this. If you have MS and are not in touch with an MS specialist what are you doing? If you are, do you really think that specialist wouldn’t know this supplement? Even if a supposedly good MS specialist doesn’t know about this compound, at the least they will look it up and tell you if it’s okay to try.

I myself don’t trust most doctors and do my own research. But I make it a point to find ones I can trust. I did a PhD in biomedical engineering and know a metric ton of biology and still wouldn’t trust myself to decide stuff like this myself. A good doctor will bring a ton of experience, a keen understanding of human physiology, and a network he can tap into for more tips. Underestimate them at your own bodily peril.

For this compound in particular, here’s my amateurish warnings already: it’s clearly hepatotoxic, it’ll likely not even have an effect (EAE models have no real relevance to human MS) and will likely interact with other drugs you take as well.

[mwbajor]

Its not that I don't trust MDs, its that I don't trust them to be at the forefront of their field.