[runnerup]

> The pressure differential between 2,200 ft and 775 ft is much smaller.

Irrelevant. The cabin pressure is controlled independently of the Earth's environmental altitude pressure.

> Probably the lower oxygen content.

That's literally exactly the same thing as the thing that I said.

[inferiorhuman]

The cabin won't be noticeably pressurized at 2,200 ft. While a 777 will pressurize the cabin slightly before takeoff the max cabin altitude is 8,000 ft. So, yes, there is a bigger change in pressure during an approach (from 8,000 ft cabin altitude to roughly the altitude of the field) than there is going into a steep dive from 2,200 ft.

[runnerup]

I might be stupid but I don’t understand what point you’re getting at?