They used to say that about email addresses. But hold my beer and I'll be back in like a month with some buggy half-assed crap that kinda does the job and only occasionally crashes the system!
Is it that simple? From a lay perspective (and granted I’m a little foggy because I actually have covid right now), I’d expect the answer is yes but with huge unintended consequences.
Ok yes, theoretically you can make something targeting the polyA tail. But everything else you body make will also get targeted because this is basically a marker of all RNA for translation.
Now making a drug that targets only viruses and not your body RNA? Possible but it is so hard not much progress has been made.