IMO alternative architectures such as ARM64 are not suitable (yet) for use on general purpose workstations, which is what I assume the OP wants.
Not because these architectures are necessarily deficient in some way, but simply that there is far too many applications that only target X86_64. Last time I tinkered with an ARM based desktop about 90% of what I wanted was there and worked well, but there were too many edge cases for me to feel comfortable recommending it.
It's a network effect thing, and it's slowly changing, but we're not quite there yet.
Not because these architectures are necessarily deficient in some way, but simply that there is far too many applications that only target X86_64. Last time I tinkered with an ARM based desktop about 90% of what I wanted was there and worked well, but there were too many edge cases for me to feel comfortable recommending it.
It's a network effect thing, and it's slowly changing, but we're not quite there yet.