[spirit557]

If your insulin is high, you can't utilize your fat stores. They are essentially locked away. You must use your glyocgen stores and glucose to fuel your brain and body. When your insulin is low and not stimulated by carbs/protein, you can utilize your fat stores and produce ketones. Your brain and body use the ketones for energy. Our brains prefer ketones over glucose when it has the choice. This is the point OP is trying to make. The article doesn't bother to mention basic human physiology of being in a fasting state vs a fed state.

If you have hyperinsulemia (massively ignored and undiagnosed in western countries), or are eating 3 meals /day + snacks with carbs and proten, or such... it is very hard for your body to have a chance to burn fat stores. Your body becomes adapted to storing energy, not burning it. Your insulin is too frequently elevated.

This huberman pdocast you link is more about athletic performance for low carb vs high carb. There's huberman podcasts covering the fact that metabolic disease and obesity is driven by high insulin too