PowerPC is one of the 11 hardware architectures on which we regularly test Blink using Qemu https://github.com/jart/blink/blob/c8dbbc8cf553680ab48d8a304... so my guess would be yes. However it depends on how old the Mac software is. Blink currently assumes modern POSIX system calls are available, e.g. fstatat(), O_CLOEXEC, etc. i.e. you currently need a host operating system published after ~2010ish. That could change in the future if we end up writing a ./configure script.