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by malfist 1245 days ago
Jesus why is he on so many diabetic meds?

He's on metformin, taking 1500mg in the morning of an extended release, and 500mg extended release in the evening. Normal dosage for this is 500mg/day. Extended release means they stay in his system for 24 hours, no reason to take it in two doses, much less take 4x the normal amount.

He's also on Acarbose, another diabetic med. The recommended dosing for this is 50mg 3 times per day and hes' taking two 200mg doses. This makes no sense, your body eliminates it quickly, halflife of 2 hours. It's also 6x the standard dose.

He's also on Rapamycin, a cancer med or organ transplant med that is immunosupressive. Standard dose is 2mg/day. He's taking 13mg twice a week.

He's also taking Testesterone 6 of 7 days of the week, and half your standard does. Total nonsense.

This guy is going to wreck his kidney and liver with these meds, put himself at high risk of infection and disrupt his endocrine system. And that's just with his prescriptions, not even examining his supplements.

All this to brag that he's as fit as an "18 year old" whatever the fuck that means. I too could probably get "fit as an 18 year old" if I were taking steroids like testosterone and exercised every day. Hell, I be you could too, and probably without the testosterone.

This is the last guy I'd listen to for longevity treatments.

5 comments

Honestly he's got some obsessive issues here. Mental health issues that he's willing to try anything to be younger. He doesn't look young in the face and very little can change that. He must be very insecure about it. The sad this is that the doctors see money, and with that much money people won't tell you no if you have terrible ideas.
People will go to extraordinary lenghts to avoid having to confront their own mortality.
From the article: "The team, led by 29-year-old regenerative medicine physician Oliver Zolman"

29-year-old physician? Did he complete medical school and his residency? Give me a break.

To be honest I'm actually surprised he's able to grow muscles at the rate at which he's doing it considering Rapamycin and Metformin are both known for really hindering muscle growth and general performance.
I mean ... he ran it by his team of 30 doctors he hired.
Team of 30 doctors lead by....a 29 year old.
I think rapamycin has some study supporting it
The data on rapamycin (and rapalogs in general) is mixed. There is no reliable evidence that it slows down biological aging in humans. Even if it does have some benefits we don't clearly understand the optimal dosing and schedule.

https://peterattiamd.com/mattkaeberlein2/

If only some kind of machine could help us figure that out! /s

200+ references in this journal article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814615/

Rapamycin to me is the bat shit crazy aspect of this.

There is no research on taking a powerful immunosuppressant pharmaceutical for the next 40 years for "longevity".

Not to mention testosterone. At least testosterone will make you feel great while you actually shorten your life in the name of longevity.