[blucz]

Some kinds of work are much easier in person, like brainstorming and high-level product design. Many other kinds of work--the ones that take up the bulk of the time in my experience--are best done alone. This includes most of the hashing-out-the-details stuff like coding, graphic design, and copy-writing.

The most important thing is finding people independent enough to function remotely. There some also work to be done in breaking down social boundaries--remote workers need to be willing to reach out immediately when they are stuck, have ideas, or need to talk something through. Many introverted people have trouble with this idea, especially at first.