The F# based WebSharper web framework: http://websharper.com/. WebSharper is based on the work of Philip Wadler, et al: http://groups.inf.ed.ac.uk/links/formlets/
Here's another article by Philip Wadler on Formlets: http://homepages.inf.ed.ac.uk/wadler/papers/formlets-aplas/f...
Of course Microsoft uses F# for Bing data processing.