[nodemaker]

I think its a cool theory and seems the most reasonable from all the other theories of aging. However I am a bit disappointed when I only see David's name on every paper published on this topic. Why dont other institutions start similar studies to verify this claim?

[carbocation]

Some say that there are issues with this and related works.

https://twitter.com/charlesmbrenner/status/16135817576344576...

[DennisP]

So he's saying they didn't fix aging, they just fixed some simpler damage they did themselves. But in a previous experiment, the same treatment improved aging damage to the vision of actually old mice:

> Sinclair and colleagues injected the reprogramming-factor genes into the eyes of 1-year-old healthy mice, roughly the mouse equivalent of middle-age. By this stage, the animals had visual acuity scores about 15% lower than their 5-month-old counterparts. Four weeks after treatment, older mice had similar acuity scores to younger ones.

https://www.science.org/content/article/researchers-restore-...

[rafaelero]

I always see this guy antagonizing everyone (David Sinclair, Aubrey de Grey, etc.). Is he the Gary Marcus of longevity?

[fallingfrog]

This is exactly the technology Altos labs is working on, and they have 4 nobel laureates on their staff. There are other companies too. There's going to be an explosion of progress in the next few years.

[rdpfeffer]

I assume the time to publish is too long, and the research too expensive. Aging takes time. Hopefully this changes soon.

[oneoff786]

Coming soon, on-demand aging.

[1970-01-01]

YC 2043: Aging as a service. AaaS.

[molotovh]

I mean ... they literally talk about the potential ability to force the aging process backward or forward in the abstract, so... haha.

[oneoff786]

Expedient prisons then. No need to serve time. You just lose 30 years on the spot.

[bpodgursky]

All the top postdocs would rather work at the well-known lab with lots of grant money and experience.

I'm sure someone else is trying, but there's an agglomerative effect here, where a competing lab would be starting at a disadvantage and playing with a B-team.