[generalizations]

Wrong title: "Loss of epigenetic information as a cause of mammalian aging"

[andrewl]

The title here is the fourth item in the list of highlights:

• Cellular responses to double-stranded DNA breaks erode the epigenetic landscape

• This loss of epigenetic information accelerates the hallmarks of aging

• These changes are reversible by epigenetic reprogramming

• By manipulating the epigenome, aging can be driven forward and backward