Some relevant articles/posts:
https://news.ycombinator.com/item?id=33732863
https://erictopol.substack.com/p/the-new-obesity-breakthroug...
https://astralcodexten.substack.com/p/semaglutidonomics
https://astralcodexten.substack.com/p/highlights-from-the-co...
https://www.worksinprogress.co/issue/the-future-of-weight-lo...
https://www.nature.com/articles/d41586-022-04505-7
https://www.nature.com/articles/s41598-020-61112-0