I have no difficulty estimating sizes and weights in kilometers, meters and centimeters, in tons, kilograms or grams, or in assessing the weather in celsius.
What I mean is that it's calibrated for humans, at least dumb ones like me.
0F, it's cold and the wind chill makes it miserable. 0C? That's 32F, which is technically freezing but I can still work on my cars outside in that weather.
100F, sweaty, hot, chugging water if you're outside. 100C? GG, you're dead.
Honestly, that's just a matter of what you're used to. All my life I used Celsius, and even the dumbest of the dumb around me would always have a pretty good idea about how hot or cold a day was based on the temperature.